The flagellin of candidate live biotherapeutic Enterococcus gallinarum MRx0518 is a potent immunostimulant
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چکیده
منابع مشابه
VanB-VanC1 Enterococcus gallinarum, Italy
Virtually all practices had a computer (79 [99%] of 80), Internet access (70 [88%] of 80), and email (53 [75%] of 71). Most (68 [91%] of 75) were comfortable using a Webbased application to submit case reports. However, because Internet access and email may not be universal, multiple modes of communication must be utilized. Furthermore, of 81 respondents, 29 (36%) indicated lack of time, and 24...
متن کاملThe first case report of Enterococcus gallinarum meningitis in neonate
RATIONALE Enterococcus gallinarum meningitis (EGM) is rarely found in normal adults and even rarer in children. To our knowledge, EGM in neonate has not been reported previously. PATIENTS CONCERNS Here we reported the first case of EGM in neonate. Prolonged fever was the only manifestation for the case after admission. DIAGNOSES Cerebrospinal fluid cultures showed that the isolate was Enter...
متن کاملEnterococcus gallinarum meningitis in an immunocompetent host: a case report.
We describe a rare case of a 53-year-old man with a long history of alcohol abuse, with Enterococcus gallinarum meningitis, an organism that rarely causes human infection and is primarily found in the gastrointestinal tract of poultry. The patient improved with high-dose ampicillin and gentamicin therapy. To our knowledge, this is the first Brazilian reported case of E. gallinarum meningitis an...
متن کاملAnalysis of peptidoglycan precursors in vancomycin-resistant Enterococcus gallinarum BM4174.
Vancomycin resistance in enterococci is an increasing clinical problem, and several phenotypes have been identified. We demonstrate here that the resistance mechanism in the constitutively vancomycin-resistant Enterococcus gallinarum BM4174 involves an altered pathway of peptidoglycan synthesis and hydrolysis of the normal precursors in the vancomycin-sensitive pathway. A ligase encoded by the ...
متن کاملvanC cluster of vancomycin-resistant Enterococcus gallinarum BM4174.
Glycopeptide-resistant enterococci of the VanC type synthesize UDP-muramyl-pentapeptide[D-Ser] for cell wall assembly and prevent synthesis of peptidoglycan precursors ending in D-Ala. The vanC cluster of Enterococcus gallinarum BM4174 consists of five genes: vanC-1, vanXY(C), vanT, vanR(C), and vanS(C). Three genes are sufficient for resistance: vanC-1 encodes a ligase that synthesizes the dip...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-018-36926-8